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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK25
All Species:
13.33
Human Site:
T274
Identified Species:
24.44
UniProt:
O00506
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00506
NP_006365.2
426
48112
T274
H
K
F
I
T
R
Y
T
K
K
T
S
F
L
T
Chimpanzee
Pan troglodytes
XP_001162228
584
64501
T432
H
K
F
I
T
R
Y
T
K
K
T
S
F
L
T
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
K285
H
P
F
V
K
S
A
K
G
V
S
I
L
R
D
Dog
Lupus familis
XP_848578
318
35396
E169
R
F
R
P
T
A
K
E
L
L
K
H
K
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2W1
426
48157
T274
H
K
F
I
T
R
Y
T
K
K
T
S
F
L
T
Rat
Rattus norvegicus
O54748
491
56103
K282
H
P
F
I
K
N
A
K
P
V
S
I
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513191
426
48196
T274
H
K
F
I
T
R
Y
T
K
K
T
S
F
L
M
Chicken
Gallus gallus
Q5ZJK4
486
55318
K284
H
P
F
V
K
S
A
K
G
A
S
I
L
R
D
Frog
Xenopus laevis
Q6IP06
493
56486
K281
H
P
F
I
K
N
A
K
P
V
S
I
L
R
D
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
K281
H
P
F
I
V
G
A
K
P
V
S
I
L
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
K297
H
E
F
I
R
N
A
K
H
R
S
I
L
K
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NB31
497
55620
P290
H
T
F
I
K
N
A
P
G
C
D
I
M
Q
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38692
1080
117043
K280
S
K
F
I
R
A
H
K
A
T
P
T
S
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
38.4
71.5
N.A.
98.5
38.4
N.A.
94.3
38.8
38.5
38.6
N.A.
29.7
N.A.
35.6
N.A.
Protein Similarity:
100
72.5
57
72.5
N.A.
99.7
55.1
N.A.
97.8
55.9
56.1
56.9
N.A.
42.1
N.A.
51.7
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
100
20
N.A.
93.3
13.3
20
20
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
100
26.6
N.A.
93.3
26.6
26.6
26.6
N.A.
40
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
54
0
8
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
31
% D
% Glu:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
8
93
0
0
0
0
0
0
0
0
0
31
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
24
0
0
0
0
0
0
% G
% His:
85
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
0
77
0
0
0
0
0
0
0
54
0
8
8
% I
% Lys:
0
39
0
0
39
0
8
54
31
31
8
0
8
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
8
0
0
47
31
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
39
0
8
0
0
0
8
24
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
8
0
16
31
0
0
0
8
0
0
0
39
0
% R
% Ser:
8
0
0
0
0
16
0
0
0
0
47
31
8
0
0
% S
% Thr:
0
8
0
0
39
0
0
31
0
8
31
8
0
0
24
% T
% Val:
0
0
0
16
8
0
0
0
0
31
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _